I Found On The Internet Not Saying These Are Confirmed
This is probably NOT the full list of weapons that will be in retail, just a few of them.
.

.357 Cowboy Rifle
9

9mm Pistol
A

All-American
Archimedes II
A cont.

Assault Rifle
C

Concrete Club
D

Dynamite
G

Golf Club
Grenade Machine Gun
P

Portable Laser Beacon
S

Single-Shot Shotgun
V

Varmint Rifle
Virgin Mary Pistol

This Info Is From The Website
Description:
Experience all the sights and sounds of fabulous New Vegas, brought to you by Vault-Tec, America's First Choice in Post Nuclear Simulation. Explore the treacherous wastes of the Great Southwest from the safety and comfort of your very own vault: Meet new people, confront terrifying creatures, and arm yourself with the latest high-tech weaponry as you make a name for yourself on a thrilling new journey across the Mojave wasteland. A word of warning, however - while Vault-Tec engineers have prepared for every contingency,* in Vegas, fortunes can change in an instant. Enjoy your stay.

Story:
Welcome to Vegas. New Vegas.

It’s the kind of town where you dig your own grave prior to being shot in the head and left for dead…and that’s before things really get ugly. It’s a town of dreamers and desperados being torn apart by warring factions vying for complete control of this desert oasis. It’s a place where the right kind of person with the right kind of weaponry can really make a name for themselves, and make more than an enemy or two along the way.

As you battle your way across the heat-blasted Mojave Wasteland, the colossal Hoover Dam, and the neon drenched Vegas Strip, you’ll be introduced to a colorful cast of characters, power-hungry factions, special weapons, mutated creatures and much more. Choose sides in the upcoming war or declare “winner takes all” and crown yourself the King of New Vegas in this follow-up to the 2008 videogame of the year, Fallout 3.

Enjoy your stay.

Key Features:
Feel the Heat in New Vegas! Not even nuclear fallout could slow the hustle of Sin City. Explore the vast expanses of the desert wastelands – from the small towns dotting the Mojave Wasteland to the bright lights of the New Vegas strip. See the Great Southwest as could only be imagined in Fallout.
Feuding Factions, Colorful Characters and a Host of Hostiles! A war is brewing between rival factions with consequences that will change the lives of all the inhabitants of New Vegas. The choices you make will bring you into contact with countless characters, creatures, allies, and foes, and determine the final explosive outcome of this epic power struggle.
New Systems! Enjoy new additions to Fallout: New Vegas such as a Companion Wheel that streamlines directing your companions, a Reputation System that tracks the consequences of your actions, and the aptly titled Hardcore Mode to separate the meek from the mighty. Special melee combat moves have been added to bring new meaning to the phrase “up close and personal”. Use V.A.T.S. to pause time in combat, target specific enemy body parts and queue up attacks, or get right to the action using the finely-tuned real-time combat mechanics.
An Arsenal of Shiny New Guns! With double the amount of weapons found in Fallout 3, you’ll have more than enough new and exciting ways to deal with the threats of the wasteland and the locals. In addition, Vault-Tec engineers have devised a new weapons configuration system that lets you tinker with your toys and see the modifications you make in real time.
Let it Ride! In a huge, open world with unlimited options you can see the sights, choose sides, or go it alone. Peacemaker or Hard Case, House Rules, or the Wild Card - it’s all in how you play the game.

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What is the release date?
Fallout: New Vegas is scheduled for a Fall 2010 release on the Xbox 360, PLAYSTATION 3, and Games for Windows in North America and Europe.

Who is developing the game?
In conjunction with Bethesda Softworks, Fallout: New Vegas is being developed by Obsidian Entertainment, the creator of award winning RPGs such as Neverwinter Nights 2. Obsidian is also led by the founders of Black Isle Studios - the developers of the original Fallout and Fallout 2.

Where does Fallout: New Vegas take place?
In and around New Vegas in Nevada.

What is Fallout New Vegas’ rating?
Currently the rating is pending, but is planned as a Mature-rated title.

What are the PC system requirements?
Closer to the release of Fallout: New Vegas, we’ll share the minimum and recommended system requirements.

Is Fallout New Vegas a Games for Windows title? Will it require Windows?
Fallout: New Vegas is a Games for Windows title. As such, you’ll be able to use an Xbox 360 controller if you choose. New Vegas will run with Windows XP, Vista, and Windows 7.

Will Fallout New Vegas include multiplayer?
No, Fallout: New Vegas is a single-player game only.

I have lots of ideas and questions, where do I send them?
We encourage you to register on our official forums and post your ideas and questions in the Fallout: New Vegas section, where our fans and developers share and discuss ideas and answer questions.

Where can I get more information on the game?
Check out our official site, fallout.bethsoft.com, where we continually update our sections for art, reviews, previews, interviews, and more. You can also visit Bethesda Blog, our Fallout Facebook page, and our company Twitter page.

Limited Collectors Edition


Fallout: New Vegas is also available as a Limited Collectors Edition, which includes:
7 Casino Chips based on casinos in New Vegas
A 'Lucky 38' Platinum Chip
A deck of cards with New Vegas related images of characters
Graphic Novel 'All Roads', about events preceding the game
Making of Fallout: New Vegas DVD
Preorder Bonuses

The following bonuses can be found exclusive to a different store in each continent. To obtain them, they must be pre-ordered from each store. [1] They can be obtained by preordering either a standard edition or Collector's Edition.
Classic Pack

Armoured Vault 13 Jumpsuit & Canteen
Weathered 10mm Pistol
5 Stimpacks
Available from EB Games in Australia and Gamestop in North America.
Tribal Pack

Tribal Raiding Armour
High Damage Broad Machete
5 Doses of Bleak Venom
10 Throwing Spears
Available from an order at Amazon.
Caravan Pack

Lightweight Leather Armour
Caravan Shotgun
4 Repair Kits
Binoculars
Available from Walmart in North America, Game in Australia and online at Steam worldwide.
Mercenary Pack

Lightweight Metal Armour
Mercenary grenade rifle
3 'Super Stimpacks'
3 Doctor's Bags

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