Number 17
In a single game, hit 4 or more home runs with the same player (not achievable in Home Run Derby; only earned if playing an uninterrupted game against the CPU, without switching sides or fast forwarding).

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This one is a little hard to do in a standard 9 inning game. For this, you should be the Away team. If you can drag out extra innings by having a tied score in the 9th, and then allowing the CPU to equal any scoring you do in the extra frames, you can play as many innings as it takes to hit 4 home runs. Once you get to the extra innings, just make quick outs with anyone that has zero home runs. Once you get a player or two with three home runs, just keep making outs until their turn to the plate comes up.

Having an entire team with maximum attributes is important and play on rookie difficulty. This will give your 9 players a chance to hit the 4 homers. It should be obvious, but the sliders you want maxed are:

Human Contact
Human Power
Human Timing
Human Sold Hits