Item description:

Quick Save right before the first boss 43 Hearts and Axe weapon. No damage taken.

You can get 2 Trophies with this save.
Vampire Killer - Clear a stage while taking no Damage.
Intercepted! - Take the crystal before it hits the ground.

So for no damage you need to kill the boss while taking no damage with the axe weapon you can cheat the boss fireball attacks Using Triangle attack, it costs 10 hearts so you should be able to cast it 5 times and have 8 spare hearts to throw axes. The boss has 3 attacks:
Dive - he will dive and grab you if he touches you but this is easy avoidable.
Fireball - He will spit a fireball that will split once it hits the ground. I was able to avoid this easily with Triangle attack and once you land you should be save from the split flames.
Rock attack thingy Again Triangle attack should save you.

This being a Quick save it will auto delete once you load it so if you get hit replace the file and try again. Once you get it done don't forget to Grab the Orb in the air Good Luck.