Item description:

Use Wire (Hold Triangle Button)

Scratches Or No Scratches trophy will unlock

Examine desk
Examine left panel of desk
Input combination – 3618
Open panel under combination lock
Pick up key
Press circle to back out to the desk
There are three drawers on the right – try to unlock the bottom one
Hold the left analogue stick right until the view changes to the right side of the desk
Examine snake
Press button on top of snake head
Press circle to go back to desk view
Hold analogue stick left until the view changes to the left side of the desk
Examine snake

Press the button at the bottom of the snake

Indicating either white or black, following a specific sequence.

That sequence is:

B / W / B / W / B / Wx3 / Bx2 / Wx2 / Bx2 / W / B

(If David says something like “that wasn't right” then the sequence
will reset and you need to start over)

You will automatically get a master key and a letter

Don't bother with the key yet,
just back out (Press O)

Running With Scissors trophy will unlock during/after cutscene